Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterisation of the cell line HC-AFW1 derived from a pediatric hepatocellular carcinoma.

PloS one - 1 Jan 2012

Armeanu-Ebinger Sorin, Wenz Julia, Seitz Guido, Leuschner Ivo, Handgretinger Rupert, Mau-Holzmann Ulrike A, Bonin Michael, Sipos Bence, Fuchs Jörg, Warmann Steven W

Abstract excerpt

Current treatment of paediatric hepatocellular carcinoma (HCC) is often inefficient due to advanced disease at diagnosis and resistance to common drugs. The aim of this study was to generate a cell line derived from a paediatric HCC in order to expand research in this field. We established the HC-AFW1 cell line from a liver neoplasm of a 4-year-old boy through culturing of primary tumor specimens. The cell line...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Hepatocellular
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Separation

Share to Cell Transformation, Neoplastic

Share to Child, Preschool

Share to Gene Expression Regulation, Neoplastic

Share to Liver Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 22666492
DOI: 10.1371/journal.pone.0038223
PMCID: PMC3364222

Genes

AFP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterisation of the cell line HC-AFW1 derived from a pediatric hepatocellular carcinoma.PMID 22666492Read ↗

Establishment and characterization of a cancer cell line derived from an aggressive childhood liver tumor.Semantic proximity Read ↗

Genomic analysis of fibrolamellar hepatocellular carcinomaSemantic proximity Read ↗

Establishment and Characterization of 7 Novel Hepatocellular Carcinoma Cell Lines from Patient-Derived Tumor XenograftsSemantic proximity Read ↗

Paediatric hepatocellular carcinoma due to somatic CTNNB1 and NFE2L2 mutations in the setting of inherited bi-allelic ABCB11 mutations.Semantic proximity Read ↗

Characterization of pediatric hepatocellular carcinoma reveals genomic heterogeneity and diverse signaling pathway activationSemantic proximity Read ↗

Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development.Semantic proximity Read ↗

An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneitySemantic proximity Read ↗

Fighting rare cancers: lessons from fibrolamellar hepatocellular carcinoma.Semantic proximity Read ↗

Clinical and immunophenotype correlating with response to immunotherapy in paediatric patients with primary liver carcinoma. A case series.Semantic proximity Read ↗

High-risk blastemal Wilms tumor can be modeled by 3D spheroid cultures in vitroSemantic proximity Read ↗

Wilms tumor primary cultures capture phenotypic heterogeneity and facilitate preclinical screeningSemantic proximity Read ↗

Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.