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Article

Differentiation potential of mesenchymal progenitor cells following transplantation into calvarial defects.

Journal of the mechanical behavior of biomedical materials - 1 Jul 2012

Schantz Jan-Thorsten, Woodruff Maria Ann, Lam Chris X F, Lim Thiam Chye, Machens Hans Gunther, Teoh Swee Hin, Hutmacher Dietmar Werner

Abstract excerpt

The complexity of stem cell lineage commitment requires studies to investigate the intrinsic and extrinsic regulatory events during differentiation. The objective of this long-term in vivo study was to investigate cellular differentiation and tissue formation of transplanted undifferentiated bone-marrow-derived mesenchymal progenitor cells (BMPCs) in combination with a medical grade polycaprolactone (mPCL)...

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Identifiers

PMID: 22658162
DOI: 10.1016/j.jmbbm.2012.02.008

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