Article
Three-dimensional printed polycaprolactone-based scaffolds provide an advantageous environment for osteogenic differentiation of human adipose-derived stem cells.
Journal of tissue engineering and regenerative medicine - 1 Jan 2018
Rumiński Sławomir, Ostrowska Barbara, Jaroszewicz Jakub, Skirecki Tomasz, Włodarski Krzysztof, Święszkowski Wojciech, Lewandowska-Szumieł Małgorzata
Abstract excerpt
The capacity of bone grafts to repair critical size defects can be greatly enhanced by the delivery of mesenchymal stem cells (MSCs). Adipose tissue is considered the most effective source of MSCs (ADSCs); however, the efficiency of bone regeneration using undifferentiated ADSCs is low. Therefore, this study proposes scaffolds based on polycaprolactone (PCL), which is widely considered a suitable MSC delivery...
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