Article
Meiotic chromosome pairing is promoted by telomere-led chromosome movements independent of bouquet formation.
PLoS genetics - 1 Jan 2012
Lee Chih-Ying, Conrad Michael N, Dresser Michael E
Abstract excerpt
Chromosome pairing in meiotic prophase is a prerequisite for the high fidelity of chromosome segregation that haploidizes the genome prior to gamete formation. In the budding yeast Saccharomyces cerevisiae, as in most multicellular eukaryotes, homologous pairing at the cytological level reflects the contemporaneous search for homology at the molecular level, where DNA double-strand broken ends find and interact...
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