Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparing enhancer action in cis and in trans.

Genetics - 1 Aug 2012

Bateman Jack R, Johnson Justine E, Locke Melissa N

Abstract excerpt

Studies from diverse systems have shown that distinct interchromosomal interactions are a central component of nuclear organization. In some cases, these interactions allow an enhancer to act in trans, modulating the expression of a gene encoded on a separate chromosome held in close proximity. Despite recent advances in uncovering such phenomena, our understanding of how a regulatory element acts on another...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HSP70 Heat-Shock Proteins
Share to Phenotype
Share to Transcriptional Activation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Transgenes

Share to Drosophila

Share to Enhancer Elements, Genetic

Share to Epistasis, Genetic

Share to Gene Expression Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 22649083
DOI: 10.1534/genetics.112.140954
PMCID: PMC3415998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparing enhancer action in cis and in trans.PMID 22649083Read ↗

Quantitative comparison of cis-regulatory element (CRE) activities in transgenic Drosophila melanogaster.Semantic proximity Read ↗

Enhancer action in trans is permitted throughout the Drosophila genome.Semantic proximity Read ↗

The role of insulators in transgene transvection in <i>Drosophila</i>Semantic proximity Read ↗

Enhancer-promoter communication at the yellow gene of Drosophila melanogaster: diverse promoters participate in and regulate trans interactions.Semantic proximity Read ↗

Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes.Semantic proximity Read ↗

Transvection in Drosophila: trans-interaction between yellow enhancers and promoter is strongly suppressed by a cis-promoter only in certain genomic regions.Semantic proximity Read ↗

Subtle changes in motif positioning cause tissue-specific effects on robustness of an enhancer's activity.Semantic proximity Read ↗

Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice.Semantic proximity Read ↗

The Drosophila gypsy insulator supports transvection in the presence of the vestigial enhancer.Semantic proximity Read ↗

Interallelic Transcriptional Enhancement as an in Vivo Measure of Transvection in Drosophila melanogaster.Semantic proximity Read ↗

Site-specific transformation of Drosophila via phiC31 integrase-mediated cassette exchange.Semantic proximity Read ↗

A massively parallel reporter assay reveals context-dependent activity of homeodomain binding sites in vivo.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.