Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Extended RET gene analysis in patients with apparently sporadic medullary thyroid cancer: clinical benefits and cost.

Hormones & cancer - 1 Aug 2012

Lindsey Susan C, Kunii Ilda S, Germano-Neto Fausto, Sittoni Misaki Y, Camacho Cléber P, Valente Flávia O F, Yang Ji H, Signorini Priscila S, Delcelo Rosana, Cerutti Janete M, Maciel Rui M B, Dias-da-Silva Magnus R

Abstract excerpt

RET sequencing has become an important tool in medullary thyroid cancer (MTC) evaluation and should be performed even in the absence of family history of MTC. The most commonly studied exons in index cases are 8, 10, 11, and 13-16. To address the ATA guidelines regarding the sequencing of the ent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Carcinoma, Neuroendocrine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Pedigree

Share to Proto-Oncogene Proteins c-ret

Share to Sequence Analysis, DNA

Share to Thyroid Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 22648435
DOI: 10.1007/s12672-012-0109-7
PMCID: PMC10358128

Genes

RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22648435-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Extended RET gene analysis in patients with apparently sporadic medullary thyroid cancer: clinical benefits and cost.PMID 22648435Read ↗

Next-Generation Sequencing in Sporadic Medullary Thyroid Cancer Patients: Mutation Profile and Disease AggressivenessSemantic proximity Read ↗

Genetic Landscape of Somatic Mutations in a Large Cohort of Sporadic Medullary Thyroid Carcinomas Studied by Next-Generation Targeted SequencingSemantic proximity Read ↗

RET genetic screening of sporadic medullary thyroid cancer (MTC) allows the preclinical diagnosis of unsuspected gene carriers and the identification of a relevant percentage of hidden familial MTC (FMTC)Semantic proximity Read ↗

RET protooncogene mutations in patients with apparently sporadic medullary thyroid carcinoma.Semantic proximity Read ↗

Detection of Molecular Alterations in Medullary Thyroid Carcinoma Using Next-Generation Sequencing: an Institutional Experience.Semantic proximity Read ↗

Combined RET and Ki-67 assessment in sporadic medullary thyroid carcinoma: a useful tool for patient risk stratification.Semantic proximity Read ↗

Sporadic and familial medullary thyroid carcinoma: state of the art.Semantic proximity Read ↗

Molecular Pathology of Hereditary and Sporadic Medullary Thyroid CarcinomasSemantic proximity Read ↗

The rare intracellular RET mutation p.Ser891Ala in an apparently sporadic medullary thyroid carcinoma: a case report and review of the literature.Semantic proximity Read ↗

Targeted DNA Sequencing Detects Mutations Related to Susceptibility among Familial Non-medullary Thyroid Cancer.Semantic proximity Read ↗

Low Prevalence of the Somatic M918T <i>RET</i> Mutation in Micro-Medullary Thyroid CancerSemantic proximity Read ↗

Molecular basis of medullary thyroid carcinoma: the role of RET polymorphisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.