Article
Association between genetic variants in adhesion molecules and outcomes after hematopoietic cell transplants.
International journal of immunogenetics - 1 Apr 2013
Thyagarajan B, Jackson S, Basu S, Jacobson P, Gross M D, Weisdorf D J, Arora M
Abstract excerpt
Allogeneic hematopoietic cell transplant (HCT) is associated with a high morbidity and mortality. Adhesion molecules play an important role in endothelial activation and initiation of inflammatory response. We hypothesized that single nucleotide polymorphisms (SNPs) in the endothelial molecules may contribute to heterogeneity in HCT outcomes. We evaluated the association of 4 SNPs in ICAM1 (rs5498), PECAM1 (rs668...
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