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Article

BDNF levels and genotype are associated with antipsychotic-induced weight gain in patients with chronic schizophrenia.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Aug 2008

Zhang Xiang Yang, Zhou Dong Feng, Wu Gui Ying, Cao Lian Yuan, Tan Yun Long, Haile Colin N, Li Jun, Lu Lin, Kosten Therese A, Kosten Thomas R

Abstract excerpt

Recent evidence suggests that centrally released brain-derived neurotrophic factor (BDNF) modulates eating behavior and metabolism that is responsible for body weight fluctuation. BDNF also may play an important role in the therapeutic action of antipsychotic medications. We investigated whether the Val66Met polymorphism of the BDNF gene affected weight gain after long-term antipsychotic treatment in...

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Source

Identifiers

PMID: 17987059
DOI: 10.1038/sj.npp.1301619

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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