[A new genetic diagnosis of familiar gastrointestinal stromal tumour].

Abstract excerpt

Gastrointestinal stromal tumours (GIST) are the most common mesenchymal tumours of the gastrointestinal tract. Familial GIST with autosomal dominant inheritance and mutation in c-KIT or PDGFR-α, are rare and characterized by multiple GIST, relatively young age at diagnosis and hyperplasia of the interstitial cells of Cajal. Around twenty families with germ line mutations in c-KIT and three families with mutations...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Proto-Oncogene Proteins c-kit
• Share to Benzamides
• Share to Fatal Outcome