Article
Molecular biology of glioma.
Advances in experimental medicine and biology - 1 Jan 2012
Marumoto Tomotoshi, Saya Hideyuki
Abstract excerpt
Glioblastoma (GBM) is the most aggressive form of glioma. Despite ceaseless efforts by researchers and physicians to find new therapeutic strategies, there have been no significant advances in the treatment of GBMs for several decades and most patients with GBM die within one and half years of diagnosis. Undoubtedly, one reason for this is the insufficient understanding of the initiation and progression of GBMs...
Topics
- Brain Neoplasms
- Epigenesis, Genetic
- Gene Expression Regulation, Neoplastic
- Glioblastoma
- Glioma
- Humans
- MicroRNAs
- Models, Genetic
- Molecular Biology
- Mutation
