Article
Single amino acid mutation in an ATP-binding cassette transporter gene causes resistance to Bt toxin Cry1Ab in the silkworm, Bombyx mori.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jun 2012
Atsumi Shogo, Miyamoto Kazuhisa, Yamamoto Kimiko, Narukawa Junko, Kawai Sawako, Sezutsu Hideki, Kobayashi Isao, Uchino Keiro, Tamura Toshiki, Mita Kazuei, Kadono-Okuda Keiko, Wada Sanae, Kanda Kohzo, Goldsmith Marian R, Noda Hiroaki
Abstract excerpt
Bt toxins derived from the arthropod bacterial pathogen Bacillus thuringiensis are widely used for insect control as insecticides or in transgenic crops. Bt resistance has been found in field populations of several lepidopteran pests and in laboratory strains selected with Bt toxin. Widespread planting of crops expressing Bt toxins has raised concerns about the potential increase of resistance mutations in...
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