Article
Parallel evolution of Bacillus thuringiensis toxin resistance in lepidoptera.
Genetics - 1 Oct 2011
Baxter Simon W, Badenes-Pérez Francisco R, Morrison Anna, Vogel Heiko, Crickmore Neil, Kain Wendy, Wang Ping, Heckel David G, Jiggins Chris D
Abstract excerpt
Despite the prominent and worldwide use of Bacillus thuringiensis (Bt) insecticidal toxins in agriculture, knowledge of the mechanism by which they kill pests remains incomplete. Here we report genetic mapping of a membrane transporter (ABCC2) to a locus controlling Bt Cry1Ac toxin resistance in two lepidopterans, implying that this protein plays a critical role in Bt function.
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