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Resistance to Bacillus thuringiensis linked with a cadherin transmembrane mutation affecting cellular trafficking in pink bollworm from China.

Insect biochemistry and molecular biology - 1 Mar 2018

Wang Ling, Ma Yuemin, Wan Peng, Liu Kaiyu, Xiao Yutao, Wang Jintao, Cong Shengbo, Xu Dong, Wu Kongming, Fabrick Jeffrey A, Li Xianchun, Tabashnik Bruce E

Abstract excerpt

Evolution of pest resistance reduces the efficacy of insecticidal proteins from the gram-positive bacterium Bacillus thuringiensis (Bt) used widely in sprays and transgenic crops. In some previously studied strains of three major lepidopteran pests, resistance to Bt toxin Cry1Ac is associated with mutations disrupting the extracellular or cytoplasmic domains of cadherin proteins that bind Cry1Ac in the midgut of...

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PMID: 29408651
DOI: 10.1016/j.ibmb.2018.01.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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