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Article

Polymorphisms at the LDLR locus may be associated with ischemic cerebrovascular disease independent of lipid profile.

Current neurovascular research - 1 Aug 2012

Lee Jiann-Der, Lee Tsong-Hai, Kuo Ya-Wen, Huang Yen-Chu, Hsu Huan-Lin, Lin Ya-Hui, Wu Chih-Ying, Huang Ying-Chih, Lee Meng, Hsiao Kuang-Ming

Abstract excerpt

The low-density lipoprotein receptor (LDLR) gene has been reported to be associated with cerebral infarction. This study aimed to explore 2 genetic LDLR variants, rs688 and rs5925, for their potential roles in cerebral infarction. This genetic association study was conducted within an isolated Taiwanese population; 815 ischemic stroke patients (431 with atherothrombotic stroke and 384 with lacunar infarction) and...

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Source

Identifiers

PMID: 22621231
DOI: 10.2174/156720212801618965

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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