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Article

The Role of Bacteria in the Pathogenesis of Ulcerative Colitis

24 Apr 2012

Abstract excerpt

Factors implicated in the pathophysiology of ulcerative colitis (UC) are an abnormal immune response, defect in intestinal epithelial barrier function, and gut microbiota. Currently, it is unclear whether specific bacterial strains are responsible for the induction of intestinal inflammation, but increased bacterial tissue invasion has been described in affected UC patients. Further, a quantitative and...

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PMID: 22619714
DOI: 10.1155/2012/704953

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