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Recent Advances in Molecular Approaches to Gut Microbiota in Inflammatory Bowel Disease

1 Jun 2009

Abstract excerpt

Inflammatory bowel diseases [IBD], ulcerative colitis [UC] and Crohn's disease [CD], are chronic intestinal disorders of unknown etiology. UC and CD are heterogeneous diseases characterized by various genetic abnormalities that lead to overly aggressive T-cell responses to a subset of commensal enteric bacteria in genetically susceptible individuals. As one of critical factors involved in pathogenesis of IBD,...

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PMID: 19519444
DOI: 10.2174/138161209788489186

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