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Article

Circulating DNA and myeloperoxidase indicate disease activity in patients with thrombotic microangiopathies

20 May 2012

Abstract excerpt

Thrombotic microangiopathies (TMAs) are a group of life-threatening disorders characterized by thrombocytopenia, fragmentation of erythrocytes, and ischemic organ damage. Genetic disorders, autoimmune disease, and cancer are risk factors for TMAs, but an additional, unknown trigger is needed to bring about acute disease. Recent studies suggest that DNA and histones are released during inflammation or infection...

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Share to Complement system in diseases
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 22611154
DOI: 10.1182/blood-2012-02-412197

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