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Article

Emerging Role of Neutrophils in the Thrombosis of Chronic Myeloproliferative Neoplasms

24 Jan 2021

Abstract excerpt

Thrombosis is a major cause of morbimortality in patients with chronic Philadelphia chromosome-negative myeloproliferative neoplasms (MPN). In the last decade, multiple lines of evidence support the role of leukocytes in thrombosis of MPN patients. Besides the increase in the number of cells, neutrophils and monocytes of MPN patients show a pro-coagulant activated phenotype. Once activated, neutrophils release...

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PMID: 33498945
DOI: 10.3390/ijms22031143

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