Phenotypic characterization of treatment-naïve childhood asthma with obesity: features of lung function, inflammation, and lipid profiles.

Abstract excerpt

PURPOSE: To characterize the multidimensional phenotype of childhood asthma associated with obesity at initial diagnosis, prior to controller therapy. METHODS: We conducted a cross-sectional study of 130 treatment-naïve children with asthma, comprising 67 with normal weight and 63 with obesity. All participants underwent spirometry, assessment of inflammatory biomarkers, and immune cell profiling. Lipid profiles...

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