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Targeting Cancer Stem Cells with Natural Products

1 Jun 2012

Abstract excerpt

The cancer stem cell (CSC) hypothesis presents a fundamentally different paradigm for cancer treatment. CSCs reflect a small fraction of tumor initiating cells capable of sustained self-renewal and differentiation to form the heterogeneous tumor bulk. In order to cure cancer, it is necessary to eliminate cancer stem cells in addition to differentiated cancer cells to decrease metastasis, reduce recurrence, and...

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PMID: 22594473
DOI: 10.2174/138945012802009062

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