Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acquisition of anoikis resistance up-regulates caveolin-1 expression in human non-small cell lung cancer cells.

Anticancer research - 1 May 2012

Halim Hasseri, Luanpitpong Sudjit, Chanvorachote Pithi

Abstract excerpt

BACKGROUND: Anoikis is a key inhibitory step in the process of cancer cell metastasis. Knowledge regarding the adaptive response resulting in resistance to anoikis may benefit the development of new therapies. MATERIALS AND METHODS: Anoikis-resistant cells were generated from anoikis-sensitive lung carcinoma cells and the underlying mechanism for this process was investigated. RESULTS: Culturing H460 cells under...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Caveolin 1
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proto-Oncogene Proteins

Share to Proto-Oncogene Proteins p21(ras)

Share to ras Proteins

Share to RNA, Small Interfering

Share to Up-Regulation

Source

Identifiers

PMID: 22593443

Genes

CAV1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acquisition of anoikis resistance up-regulates caveolin-1 expression in human non-small cell lung cancer cells.PMID 22593443Read ↗

Caveolin-1 Confers Resistance of Hepatoma Cells to Anoikis by Activating IGF-1 Pathway.Semantic proximity Read ↗

Anoikis resistance in Cancer: Mechanisms, therapeutic strategies, potential targets, and models for enhanced understandingSemantic proximity Read ↗

Understanding and targeting anoikis in metastasis for cancer therapiesSemantic proximity Read ↗

Resistance to EGFR inhibitors in lung cancer occurs through horizontal transfer and is associated with increased caveolins expressionSemantic proximity Read ↗

Acquisition of anoikis resistance promotes the emergence of oncogenic K-ras mutations in colorectal cancer cells and stimulates their tumorigenicity in vivo.Semantic proximity Read ↗

Role of caveolin-1 as a biomarker for radiation resistance and tumor aggression in lung cancerSemantic proximity Read ↗

Anoikis and metastatic potential of cloudman S91 melanoma cells.Semantic proximity Read ↗

Inhibition of the Caveolin-1 pathway promotes apoptosis and overcomes pan-tyrosine kinase inhibitor resistance in hepatocellular carcinomaSemantic proximity Read ↗

Caveolin‐1 is an Important Factor for the Metastasis and Proliferation of Human Small Cell Lung Cancer NCI‐H446 CellSemantic proximity Read ↗

Overcoming anoikis – pathways to anchorage-independent growth in cancerSemantic proximity Read ↗

STAT3 mediates resistance to anoikis and promotes invasiveness of nasopharyngeal cancer cells.Semantic proximity Read ↗

Jorunnamycin A from Xestospongia sp. Suppresses Epithelial to Mesenchymal Transition and Sensitizes Anoikis in Human Lung Cancer CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.