Article
Large-scale gene disruption in Magnaporthe oryzae identifies MC69, a secreted protein required for infection by monocot and dicot fungal pathogens.
PLoS pathogens - 1 Jan 2012
Saitoh Hiromasa, Fujisawa Shizuko, Mitsuoka Chikako, Ito Akiko, Hirabuchi Akiko, Ikeda Kyoko, Irieda Hiroki, Yoshino Kae, Yoshida Kentaro, Matsumura Hideo, Tosa Yukio, Win Joe, Kamoun Sophien, Takano Yoshitaka, Terauchi Ryohei
Abstract excerpt
To search for virulence effector genes of the rice blast fungus, Magnaporthe oryzae, we carried out a large-scale targeted disruption of genes for 78 putative secreted proteins that are expressed during the early stages of infection of M. oryzae. Disruption of the majority of genes did not affect growth, conidiation, or pathogenicity of M. oryzae. One exception was the gene MC69. The mc69 mutant showed a severe...
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