Article
A putative MAP kinase kinase kinase, MCK1, is required for cell wall integrity and pathogenicity of the rice blast fungus, Magnaporthe oryzae.
Molecular plant-microbe interactions : MPMI - 1 May 2008
Jeon Junhyun, Goh Jaeduk, Yoo Sungyong, Chi Myoung-Hwan, Choi Jaehyuk, Rho Hee-Sool, Park Jongsun, Han Seong-Sook, Kim Byeong Ryun, Park Sook-Young, Kim Soonok, Lee Yong-Hwan
Abstract excerpt
Insertional mutagenesis of Magnaporthe oryzae led to the identification of MCK1, a pathogenicity gene predicted to encode mitogen-activated protein kinase kinase kinase (MAPKKK) homologous to BCK1 in Saccharomyces cerevisiae. Targeted disruption of MCK1 resulted in the fungus undergoing autolysis and showing hypersensitivity to cell-wall-degrading enzyme. The mck1 produced significantly reduced numbers of conidia...
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