Article
Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary for rice blast disease.
Proceedings of the National Academy of Sciences of the United States of America - 15 Sept 2009
Kershaw Michael J, Talbot Nicholas J
Abstract excerpt
To cause rice blast disease, the fungus Magnaporthe oryzae elaborates specialized infection structures called appressoria, which use enormous turgor to rupture the tough outer cuticle of a rice leaf. Here, we report the generation of a set of 22 isogenic M. oryzae mutants each differing by a single component of the predicted autophagic machinery of the fungus. Analysis of this set of targeted deletion mutants...
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