Article
Identification of additional coat-scaffolding interactions in a bacteriophage P22 mutant defective in maturation.
Journal of virology - 1 Apr 2000
Thuman-Commike P A, Greene B, Jakana J, McGough A, Prevelige P E, Chiu W
Abstract excerpt
Scaffolding proteins play a critical role in the assembly of certain viruses by directing the formation and maturation of a precursor capsid. Using electron cryomicroscopy difference mapping, we have identified an altered arrangement of a mutant scaffolding within the bacteriophage P22 procapsid. This mutant scaffolding allows us to directly visualize scaffolding density within the P22 procapsid. Based on these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
