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Molecular tracing of the emergence, adaptation, and transmission of hospital-associated methicillin-resistant <i>Staphylococcus aureus</i>

14 May 2012

Abstract excerpt

Hospital-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are a global health burden dominated by a small number of bacterial clones. The pandemic EMRSA-16 clone (ST36-II) has been widespread in UK hospitals for 20 y, but its evolutionary origin and the molecular basis for its hospital association are unclear. We carried out a Bayesian phylogenetic reconstruction on the basis of...

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PMID: 22586109
DOI: 10.1073/pnas.1202869109

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