Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomics and proteomics of vertebrate cholesterol ester lipase (LIPA) and cholesterol 25-hydroxylase (CH25H)

2 Aug 2011

Abstract excerpt

Cholesterol ester lipase (LIPA; EC 3.1.1.13) and cholesterol 25-hydroxylase (CH25H; EC 1.14.99.48) play essential role in cholesterol metabolism in the body by hydrolysing cholesteryl esters and triglycerides within lysosomes (LIPA) and catalysing the formation of 25-hydroxycholesterol from cholesterol (CH25H) which acts to repress cholesterol biosynthesis. Bioinformatic methods were used to predict the amino...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Proteomics Techniques and Applications
Share to Cholesterol and Lipid Metabolism
Share to Lipid metabolism and biosynthesis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22582164
DOI: 10.1007/s13205-011-0013-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomics and proteomics of vertebrate cholesterol ester lipase (LIPA) and cholesterol 25-hydroxylase (CH25H)PMID 22582164Read ↗

Evolution of the Cholesterol Biosynthesis Pathway in AnimalsSemantic proximity Read ↗

Vertebrate patatin-like phospholipase domain-containing protein 4 (PNPLA4) genes and proteins: a gene with a role in retinol metabolismSemantic proximity Read ↗

Genomic Organization of the Human Lysosomal Acid Lipase Gene (LIPA)Semantic proximity Read ↗

hLGDB: a database of human lysosomal genes and their regulationSemantic proximity Read ↗

Lysosomal acid lipase deficiency: A hidden disease among cohorts of familial hypercholesterolemia?Semantic proximity Read ↗

First LIPA Mutational Analysis in Egyptian Patients Reveals One Novel Variant: Wolman Disease.Semantic proximity Read ↗

Evolutionary aspects of lipoxygenases and genetic diversity of human leukotriene signaling.Semantic proximity Read ↗

Bioinformatics analysis identifies sequence determinants of enzymatic activity for the PHARC associated lipase ABHD12Semantic proximity Read ↗

Identification and metabolic profiling of patients with lysosomal acid lipase deficiency.Semantic proximity Read ↗

Gain and loss events in the evolution of the apolipoprotein family in vertebrataSemantic proximity Read ↗

Lipins: multifunctional lipid metabolism proteins.Semantic proximity Read ↗

Liverbase: A Comprehensive View of Human Liver BiologySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.