Dopamine acts through Cryptochrome to promote acute arousal in Drosophila.

Abstract excerpt

The fruit fly, Drosophila melanogaster, is generally diurnal, but a few mutant strains, such as the circadian clock mutant Clk(Jrk), have been described as nocturnal. We report here that increased nighttime activity of Clk mutants is mediated by high levels of the circadian photoreceptor CRYPTOCHROME (CRY) in large ventral lateral neurons (l-LN(v)s). We found that CRY expression is also required for nighttime...

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