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Article

The combination of hydrogen/deuterium exchange or chemical cross-linking techniques with mass spectrometry: mapping of human 14-3-3ζ homodimer interface.

Journal of structural biology - 1 Jul 2012

Haladová Kateřina, Mrázek Hynek, Ječmen Tomáš, Halada Petr, Man Petr, Novák Petr, Chmelík Josef, Obšil Tomáš, Šulc Miroslav

Abstract excerpt

Hydrogen/deuterium (H/D) exchange or chemical cross-linking by soluble carbodiimide (EDC) was employed in combination with high-resolution mass spectrometry (MS) to extend our knowledge about contact surface regions involved in the well-characterized model of interaction between two molecules of human 14-3-3ζ regulatory protein. The H/D exchange experiment provided low resolution mapping of interaction in the...

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PMID: 22580067
DOI: 10.1016/j.jsb.2012.04.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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