Article
Specific amino acids affecting Drosophila melanogaster prophenoloxidase activity in vitro.
Developmental and comparative immunology - 1 Sept 2012
Chen Yang, Liu Fei, Yang Bing, Lu Anrui, Wang Shiwei, Wang Jingfang, Ling Qing-Zhi, Li Xuan, Beerntsen Brenda T, Ling Erjun
Abstract excerpt
Insect prophenoloxidase (PPO) is a key enzyme that induces melanization around invading pathogens and at wounds to prevent further infection. Drosophila melanogaster has three PPO genes which have different biochemical properties following over-expression in S2 cells. As shown by automatic melanization of S2 cells, recombinant PPO3 (rPPO3) became activated upon Cu(2+) addition (Cu(2+)-aided cells melanization...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.