Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Formation of disulfide bonds in insect prophenoloxidase enhances immunity through improving enzyme activity and stability.

Developmental and comparative immunology - 1 Jun 2014

Lu Anrui, Peng Qin, Ling Erjun

Abstract excerpt

Type 3 copper proteins, including insect prophenoloxidase (PPO), contain two copper atoms in the active site pocket and can oxidize phenols. Insect PPO plays an important role in immunity. Insects and other invertebrates show limited recovery from pathogen invasion and wounds if phenoloxidase (PO) activity is low. In most insect PPOs, two disulfide bonds are present near the C-terminus. However, in Pimpla...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catechol Oxidase
Share to Copper
Share to Enzyme Precursors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Enzyme Stability

Share to Gram-Positive Bacterial Infections

Share to Immunity

Share to Insect Proteins

Source

Identifiers

PMID: 24480295
DOI: 10.1016/j.dci.2014.01.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Formation of disulfide bonds in insect prophenoloxidase enhances immunity through improving enzyme activity and stability.PMID 24480295Read ↗

Crystal structure of a clip-domain serine protease and functional roles of the clip domains.Semantic proximity Read ↗

The Roles of Two Clip Domain Serine Proteases in Innate Immune Responses of the Malaria Vector Anopheles gambiaeSemantic proximity Read ↗

Analysis of thioester-containing proteins during the innate immune response of Drosophila melanogaster.Semantic proximity Read ↗

Cuticular protein defective Bamboo mutant of Bombyx mori is sensitive to environmental stresses.Semantic proximity Read ↗

Characterization of expression, activity and role in antibacterial immunity of Anopheles gambiae lysozyme c-1Semantic proximity Read ↗

Functions of Manduca sexta hemolymph proteinases HP6 and HP8 in two innate immune pathways.Semantic proximity Read ↗

The Black cells phenotype is caused by a point mutation in the Drosophila pro-phenoloxidase 1 gene that triggers melanization and hematopoietic defects.Semantic proximity Read ↗

The serine protease homolog CLIPA14 modulates the intensity of the immune response in the mosquito Anopheles gambiaeSemantic proximity Read ↗

Disulfide bonds of phospholipase A2 from bee venom yield discrete contributions to its conformational stability.Semantic proximity Read ↗

Purification and characterization of Bacillus thuringiensis var. tenebrionis insecticidal proteins produced in E. coli.Semantic proximity Read ↗

The Drosophila Thioester containing Protein-4 participates in the induction of the cellular immune response to the pathogen Photorhabdus.Semantic proximity Read ↗

Specific amino acids affecting Drosophila melanogaster prophenoloxidase activity in vitro.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.