Article
Characterization of non-oxidative transaldolase and transketolase enzymes in the pentose phosphate pathway with regard to xylose utilization by recombinant Saccharomyces cerevisiae.
Enzyme and microbial technology - 10 Jun 2012
Matsushika Akinori, Goshima Tetsuya, Fujii Tatsuya, Inoue Hiroyuki, Sawayama Shigeki, Yano Shinichi
Abstract excerpt
The activity of transaldolase and transketolase, key enzymes in the non-oxidative pentose phosphate pathway, is rate-limiting for xylose utilization in recombinant Saccharomyces cerevisiae. Overexpression of TAL1 and TKL1, the major transaldolase and transketolase genes, increases the flux from the pentose phosphate pathway into the glycolytic pathway. However, the functional roles of NQM1 and TKL2, the secondary...
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