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Article

Cognitive-behavioral phenotypes of Williams syndrome are associated with genetic variation in the GTF2I gene, in a healthy population.

BMC neuroscience - 28 Nov 2014

Crespi Bernard J, Hurd Peter L

Abstract excerpt

BACKGROUND: Individuals with Williams syndrome, a neurogenetic condition caused by deletion of a set of genes at chromosomal location 7q11.23, exhibit a remarkable suite of traits including hypersociality with high, nonselective friendliness and low social anxiety, expressive language relatively well-developed but under-developed social-communication skills overall, and reduced visual-spatial abilities. Deletions...

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Source

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Identifiers

PMID: 25429715
DOI: 10.1186/s12868-014-0127-1
PMCID: PMC4247780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cognitive-behavioral phenotypes of Williams syndrome are associated with genetic variation in the GTF2I gene, in a healthy population.PMID 25429715Read ↗

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The Williams syndrome prosociality gene GTF2I mediates oxytocin reactivity and social anxiety in a healthy population.Semantic proximity Read ↗

A Common Polymorphism in a Williams Syndrome Gene Predicts Amygdala Reactivity and Extraversion in Healthy Adults.Semantic proximity Read ↗

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Anxious, hypoactive phenotype combined with motor deficits in Gtf2ird1 null mouse model relevant to Williams syndrome.Semantic proximity Read ↗

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