Article
MAP3K7 and GSTZ1 are associated with human longevity: a two-stage case-control study using a multilocus genotyping.
Age (Dordrecht, Netherlands) - 1 Aug 2013
Di Cianni Fausta, Campa Daniele, Tallaro Federica, Rizzato Cosmeri, De Rango Francesco, Barale Roberto, Passarino Giuseppe, Canzian Federico, Gemignani Federica, Montesanto Alberto, Landi Stefano, Rose Giuseppina
Abstract excerpt
The pathways that regulate energy homeostasis, the mechanisms of damage repair, and the signaling response to internal environmental changes or external signals have been shown to be critical in modulating lifespan of model organisms and humans. In order to investigate whether genetic variation of genes involved in these pathways contribute to longevity, a two-stage case-control study in two independent sets of...
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