Identification of an amino acid substitution in the benA, beta-tubulin gene of Aspergillus nidulans that confers thiabendazole resistance and benomyl supersensitivity.

doi:10.1002/cm.970170204

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Article

Identification of an amino acid substitution in the benA, beta-tubulin gene of Aspergillus nidulans that confers thiabendazole resistance and benomyl supersensitivity.

Cell motility and the cytoskeleton - 1 Jan 1990

Jung M K, Oakley B R

Abstract excerpt

We are using molecular genetic techniques to identify sites of interaction of beta-tubulin with benzimidizole anti-microtubule agents. We have developed a marker-rescue technique for cloning mutant alleles of the benA, beta-tubulin gene of Aspergillus nidulans and have used the technique to clone...

Topics

Alleles
Amino Acid Sequence
Aspergillus nidulans
Base Sequence
Benomyl
Cloning, Molecular
Drug Resistance, Microbial
Genes, Fungal
Molecular Structure
Mutation
Thiabendazole
Tubulin

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