Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of an amino acid substitution in the benA, beta-tubulin gene of Aspergillus nidulans that confers thiabendazole resistance and benomyl supersensitivity.

Cell motility and the cytoskeleton - 1 Jan 1990

Jung M K, Oakley B R

Abstract excerpt

We are using molecular genetic techniques to identify sites of interaction of beta-tubulin with benzimidizole anti-microtubule agents. We have developed a marker-rescue technique for cloning mutant alleles of the benA, beta-tubulin gene of Aspergillus nidulans and have used the technique to clone two mutant benA alleles, benA16 and benA19. These are the only A. nidulans alleles known to confer resistance to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Amino Acid Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to Cloning, Molecular

Share to Drug Resistance, Microbial

Share to Genes, Fungal

Share to Molecular Structure

Share to Mutation

Source

Identifiers

PMID: 2257633
DOI: 10.1002/cm.970170204

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of an amino acid substitution in the benA, beta-tubulin gene of Aspergillus nidulans that confers thiabendazole resistance and benomyl supersensitivity.PMID 2257633Read ↗

Amino acid alterations in the benA (beta-tubulin) gene of Aspergillus nidulans that confer benomyl resistance.Semantic proximity Read ↗

Mitosis in wild-type and beta-tubulin mutant strains of Aspergillus nidulans.Semantic proximity Read ↗

Isolation and characterization of a benomyl-resistant form of beta-tubulin-encoding gene from the phytopathogenic fungus Botryotinia fuckeliana.Semantic proximity Read ↗

Yeast mutants sensitive to antimicrotubule drugs define three genes that affect microtubule function.Semantic proximity Read ↗

Molecular basis for determining the sensitivity of eucaryotes to the antimitotic drug rhizoxin.Semantic proximity Read ↗

Evaluating beta-tubulin variants as predictors of benzimidazole resistance across Caenorhabditis nematodes.Semantic proximity Read ↗

Cloning and functional analysis of a beta-tubulin gene from a benomyl resistant mutant of Aspergillus parasiticus.Semantic proximity Read ↗

Molecular analysis of the Septoria nodorum beta-tubulin gene and characterization of a benomyl-resistance mutation.Semantic proximity Read ↗

An alpha tubulin mutation suppresses nuclear migration mutations in Aspergillus nidulans.Semantic proximity Read ↗

Dual Impact of a Benzimidazole Resistant β-Tubulin on Microtubule Behavior in Fission Yeast.Semantic proximity Read ↗

Identification of a novel point mutation in the β-tubulin gene of Botrytis cinerea and detection of benzimidazole resistance by a diagnostic PCR-RFLP assaySemantic proximity Read ↗

Characterization of mutations in the beta-tubulin gene of benomyl-resistant field strains of Venturia inaequalis and other plant pathogenic fungiSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.