Article
Amino acid alterations in the benA (beta-tubulin) gene of Aspergillus nidulans that confer benomyl resistance.
Cell motility and the cytoskeleton - 1 Jan 1992
Jung M K, Wilder I B, Oakley B R
Abstract excerpt
We report the cloning and sequencing of 18 mutant alleles of the benA, beta-tubulin gene of Aspergillus nidulans that confer resistance to the benzimidazole antifungal, antimicrotubule compounds benomyl, carbendazim, nocodazole, and thiabendazole. In 12 cases, amino acid 6 was changed from histidine to tyrosine or leucine. In four cases, amino acid 198 was changed from glutamic acid to aspartic acid, glutamine,...
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