Article
Predictive mutational bioinformatic analysis of variation in the skin and wool associated corneodesmosin (CDSN) gene in sheep.
Animal science journal = Nihon chikusan Gakkaiho - 1 May 2012
Siva Subramaniam Nitthiya, Morgan Eleanor, Bottomley Steven, Tay Sharon, Gregg Keith, Lee Chee Yang, Wetherall John, Groth David
Abstract excerpt
Corneodesmosin (CDSN) is an important component of the desmosome in the epidermal cornified stratum and inner root sheath of hair follicles. DNA from a sheep BAC clone previously identified by us to contain CDSN was PCR amplified using cattle-derived primers and the product sequenced. A region of 4579 bp containing CDSN was shown to contain two exons separated by one intron and spanning 3683 bp. The DNA encodes a...
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