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A conditional multi-trait sequence GWAS discovers pleiotropic candidate genes and variants for sheep wool, skin wrinkle and breech cover traits.

Genetics, selection, evolution : GSE - 8 Jul 2021

Bolormaa Sunduimijid, Swan Andrew A, Stothard Paul, Khansefid Majid, Moghaddar Nasir, Duijvesteijn Naomi, van der Werf Julius H J, Daetwyler Hans D, MacLeod Iona M

Abstract excerpt

BACKGROUND: Imputation to whole-genome sequence is now possible in large sheep populations. It is therefore of interest to use this data in genome-wide association studies (GWAS) to investigate putative causal variants and genes that underpin economically important traits. Merino wool is globally sought after for luxury fabrics, but some key wool quality attributes are unfavourably correlated with the...

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Identifiers

PMID: 34238208
DOI: 10.1186/s12711-021-00651-0
PMCID: PMC8268212

Genes

HAS2
MAT1A

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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