Article
Crystal structure of the cysteine desulfurase DndA from Streptomyces lividans which is involved in DNA phosphorothioation.
PloS one - 1 Jan 2012
Chen Fukun, Zhang Zhenyi, Lin Kui, Qian Tianle, Zhang Yan, You Delin, He Xinyi, Wang Zhijun, Liang Jingdan, Deng Zixin, Wu Geng
Abstract excerpt
DNA phosphorothioation is widespread among prokaryotes, and might function to restrict gene transfer among different kinds of bacteria. There has been little investigation into the structural mechanism of the DNA phosphorothioation process. DndA is a cysteine desulfurase which is involved in the first step of DNA phosphorothioation. In this study, we determined the crystal structure of Streptomyces lividans DndA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
