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Article

Combined effect of prenatal solvent exposure and GSTT1 or GSTM1 polymorphisms in the risk of birth defects.

Birth defects research. Part A, Clinical and molecular teratology - 1 Jun 2012

Garlantézec Ronan, Chevrier Cécile, Coiffec Isabelle, Celebi Catherine, Cordier Sylvaine

Abstract excerpt

Exposure to solvents during pregnancy has long been suspected to increase the risk of congenital malformations. Glutathione S-transferases (GSTs) are enzymes essential for the detoxification of various chemicals. Our objective here was to assess whether GST polymorphisms might modify the association between maternal solvent exposure and the risk of birth defects. A prospective cohort included 3421 pregnant women...

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Source

Identifiers

PMID: 22570144
DOI: 10.1002/bdra.23018

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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