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Article

Determining the repertoire of immunodominant proteins via whole-genome amplification of intracellular pathogens.

PloS one - 1 Jan 2012

Dark Michael J, Lundgren Anna M, Barbet Anthony F

Abstract excerpt

Culturing many obligate intracellular bacteria is difficult or impossible. However, these organisms have numerous adaptations allowing for infection persistence and immune system evasion, making them some of the most interesting to study. Recent advancements in genome sequencing, pyrosequencing and Phi29 amplification, have allowed for examination of whole-genome sequences of intracellular bacteria without...

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PMID: 22558468
DOI: 10.1371/journal.pone.0036456
PMCID: PMC3340345

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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