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Article

Loss of sex and age driven differences in the gut microbiome characterize arthritis-susceptible 0401 mice but not arthritis-resistant 0402 mice.

PloS one - 1 Jan 2012

Gomez Andres, Luckey David, Yeoman Carl J, Marietta Eric V, Berg Miller Margret E, Murray Joseph A, White Bryan A, Taneja Veena

Abstract excerpt

BACKGROUND: HLA-DRB1 0401 is associated with susceptibility, while HLA-DRB1 0402 is associated with resistance to developing rheumatoid arthritis (RA) and collagen-induced arthritis in humans and transgenic mice respectively. The influence of gut-joint axis has been suggested in RA, though not yet proven. METHODOLOGY/PRINCIPAL FINDINGS: We have used HLA transgenic mice carrying arthritis susceptible and...

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Identifiers

PMID: 22553482
DOI: 10.1371/journal.pone.0036095
PMCID: PMC3338357

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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