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Lipid Peroxidation and Immune Biomarkers Are Associated with Major Depression and Its Phenotypes, Including Treatment-Resistant Depression and Melancholia.

Neurotoxicity research - 1 Feb 2018

Sowa-Kućma Magdalena, Styczeń Krzysztof, Siwek Marcin, Misztak Paulina, Nowak Rafał J, Dudek Dominika, Rybakowski Janusz K, Nowak Gabriel, Maes Michael

Abstract excerpt

To examine immune-inflammatory and oxidative (I&O) biomarkers in major depression (MDD) and its related phenotypes, we recruited 114 well-phenotyped depressed patients and 50 healthy controls and measured serum levels of interleukin (IL)-1α, soluble IL-1 receptor antagonist (sIL-1RA), soluble IL-2 receptor (sIL-2R), soluble IL-6 receptor (sIL-6R), soluble tumor necrosis factor receptor 60 and 80 kDa (sTNF-R1/R2),...

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PMID: 29103192
DOI: 10.1007/s12640-017-9835-5
PMCID: PMC5766730

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TRD

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