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Article

A diagnostic informatics approach for stratifying risk outcome based on combined genotype effects.

Therapeutic drug monitoring - 1 Jun 2012

Yang Lu, Valdes Roland, Taubert Dirk, Linder Mark W

Abstract excerpt

BACKGROUND: Diagnostic informatics (DI) in the context of personalized medicine involves the integration of molecular information to provide "actionable" diagnostic and therapeutic strategies. In many cases, retrospective predictions of clinical outcomes affected by multiple genes are complicated by not having the relevant genes measured within the same study. Multiplicative effect modeling is a statistical...

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PMID: 22549497
DOI: 10.1097/FTD.0b013e31824cf0ca

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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