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Article

Risk of repeated Moraxella catarrhalis colonization is increased in children with Toll-like receptor 4 Asp299Gly polymorphism.

The Pediatric infectious disease journal - 1 Nov 2013

Vuononvirta Juho, Peltola Ville, Mertsola Jussi, He Qiushui

Abstract excerpt

BACKGROUND: Moraxella catarrhalis is a common causative agent of acute otitis media and other respiratory infections in children. Toll-like receptor (TLR) 4 is an important protein of human innate immunity. One polymorphic site Asp299Gly of TLR4 is proven to result in an impaired response to lipopolysaccharide from Gram-negative bacteria. We investigated whether Finnish children who carry Asp299Gly had increased...

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Source

Identifiers

PMID: 24141797
DOI: 10.1097/INF.0b013e31829e6df2

Genes

TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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