Article
PM10-induced hospital admissions for asthma and chronic obstructive pulmonary disease: the modifying effect of individual characteristics.
Epidemiology (Cambridge, Mass.) - 1 Jul 2012
Canova Cristina, Dunster Christina, Kelly Frank J, Minelli Cosetta, Shah Pallav L, Caneja Cielito, Tumilty Michael K, Burney Peter
Abstract excerpt
BACKGROUND: Evidence suggests that oxidative stress is a unifying feature underlying the toxic actions of particulate matter (PM). We have investigated whether individual plasma antioxidant concentrations (uric acid and vitamins C, A, and E) and 10 antioxidant genes modify the response to PM with respect to hospital admissions for chronic obstructive pulmonary disease (COPD) or asthma. METHODS: Using a...
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