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<i>Toxoplasma gondii</i> tachyzoites cross retinal endothelium assisted by intercellular adhesion molecule‐1 <i>in vitro</i>

24 Apr 2012

Abstract excerpt

Retinal infection is the most common clinical manifestation of toxoplasmosis. The route by which circulating Toxoplasma gondii tachyzoites cross the vascular endothelium to enter the human retina is unknown. Convincing studies using murine encephalitis models have strongly implicated leukocyte taxis as one pathway used by the parasite to access target organs. To establish whether tachyzoites might also interact...

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PMID: 22525368
DOI: 10.1038/icb.2012.21

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