Article
Refined prediction of week 12 response and SVR based on week 4 response in HCV genotype 1 patients treated with peginterferon alfa-2a (40KD) and ribavirin.
Journal of hepatology - 1 Jun 2012
Marcellin Patrick, Reau Nancy, Ferenci Peter, Hadziyannis Stephanos, Messinger Diethelm, Tatsch Fernando, Jensen Donald
Abstract excerpt
BACKGROUND & AIMS: It is unclear whether the magnitude of reduction in hepatitis C virus (HCV) RNA between baseline and week 4 of treatment influences the probability of achieving a sustained virological response (SVR) in patients without a week 4 rapid virological response (RVR). METHODS: Data were retrospectively analyzed from two studies in which treatment-naive patients received peginterferon alfa-2a (40KD)...
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