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Article

A two-platform design for next generation genome-wide association studies.

Genetic epidemiology - 1 May 2012

Sampson Joshua N, Jacobs Kevin, Wang Zhaoming, Yeager Meredith, Chanock Stephen, Chatterjee Nilanjan

Abstract excerpt

Genome-wide association studies (GWAS) have been successful in their search for common genetic variants associated with complex traits and diseases. With new advances in array technologies together with available genetic reference sets, the next generation of GWAS will extend the search for associations with uncommon SNPs (1% ≤ MAF ≤ 10%). Two possible approaches are genotyping all participants, a prohibitively...

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PMID: 22508365
DOI: 10.1002/gepi.21634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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