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Article

Targeted therapy of acute myeloid leukemia in 2012: towards individualized therapy.

Hematology (Amsterdam, Netherlands) - 1 Apr 2012

Foran James M

Abstract excerpt

Advances in molecular diagnostics in acute myeloid leukemia (AML) have translated into significant advances in our understanding of disease prognosis and biology, and the identification of new targets for therapy. The best described of these are mutations in Fms-like tyrosine kinase 3, nucleophosmin 1, and CCAAT enhancer-binding protein-alpha in those with cytogenetically AML, which allow more accurate risk...

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Source

Identifiers

PMID: 22507802
DOI: 10.1179/102453312X13336169156456

Genes

FLT3
CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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